Research Projects
Our research began with a breakthrough in tracking brain microvascular changes in mice using advanced optical imaging techniques. We developed a suite of methods leveraging optical coherence tomography (OCT) to monitor vascular structure, blood flow, and network topology in the aging brain.
Our suite of methods leveraging optical coherence tomography (OCT) allowed us to observe how blood vessel degeneration correlates with neurodegenerative diseases like Alzheimer's, revealing that vascular decline occurs long before cognitive symptoms emerge. Now, we are translating these findings into clinical applications by integrating AI-driven retinal imaging as an early screening tool for neurodegenerative diseases. Our goal is to develop a simple, affordable eye scan that can assess an individual’s risk years in advance, enabling earlier intervention and reducing the burden of diseases like Alzheimer's and Parkinson’s. By bridging cutting-edge vascular research in animals with real-world clinical technology, we aim to revolutionize early detection and prevention strategies in neurological health.
