Timely detection and monitoring of microbes is key to the effective treatment of infection, allowing for appropriate initiation of treatment and accurate dosing. Together, smart and localized antimicrobial delivery systems coupled with real-time, sensitive microbial detection allows for superior treatment of infections. In addition to our work on antimicrobial drug delivery, we are developing new sensing techniques to detect bacteria and fungi in a variety of physiological environments, including wounds. We are interested in both quantitative detection of microbes using electrochemical sensors as well as colorimetric indicators of infection that can be used for rapid diagnosis without the need for external equipment.