Our research focuses on developing a next-generation retinal prosthesis using plasmonic nanorods and near-infrared (NIR) light to restore vision in individuals with degenerative eye diseases such as age-related macular degeneration and retinitis pigmentosa. In animal studies, we demonstrated that intravitreally injected gold nanorods, conjugated with anti-Thy1 antibodies, selectively bind to retinal neurons and enable precise neural activation through patterned NIR laser stimulation. This innovative approach allows for high-resolution, minimally invasive vision restoration without the need for implanted electrodes or genetic modification. Building on these findings, we are now working to translate this technology into clinical applications by developing a non-invasive retinal prosthesis that can be administered via simple eye injections and controlled using wearable NIR projection devices. This effort aims to provide a safer, more accessible solution for patients suffering from vision loss, bringing us closer to a breakthrough in sight restoration technology.